Force Plesk to use vhost.conf for a single domain.

/usr/local/psa/admin/sbin/httpdmng --reconfigure-domain mydomain.com

A lot easier than creating a temporary protected directory, don’t you think?

EDIT:

On SB4 use:

/usr/local/psa/admin/sbin/websrvmng --reconfigure-vhost --vhost-name=mydomain.com